Figure 7. Blood velocity profiling in FLNA ^{Δ ECS} and wt mice.

1. Graph shows the individual blood velocity profile determined by MRI over time in 4 wt mice (shades of gray) and 5 FLNA^ΔECS mice (shades of red). The mouse shown in dotted purple line is clearly an outlier within the FLNA^ΔECS cohort. Aortic velocity waveform represents velocity during different stages of cardiac cycle. A significant reduction in velocity was observed at 40 ms in the systolic cycle.
2. Representative wt (top) and FLNA^ΔECS (below) mice showing the blood flow just above the aortic valve. Note: Reduced blood flow in FLNA^ΔECS mouse as depicted by pseudocoloring. The red circle represents the time window at which the images are shown.