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Lithium dependence of glycine transport of wild-type GlyTs and mutant transporters. (A,B) COS7 cells expressing wild-type GlyT2 or GlyT2-E650M (A) or wild-type GlyT1 or GlyT1-M475E (B) were assayed for 3[H]-glycine transport in HBS containing 30 mM NaCl concentration in every point and the indicated increased LiCl concentration up to 150 mM that was reached by isotonic supplementation with choline chloride. ∗p < 0.05 Mann–Whitney test.
