Table 2.

Coefficients and standard error of the linear mixed-effects model for the optically derived outcome variables ScO₂, OEF, BFI, and CMRO_2,i.

Outcome Variable	Estimate (SE) of Coefficient	P value
ScO2, %
Intercept	50.7 (2.2)	<0.0001
Time, hr	−0.09 (0.04)	0.02
Cardiac Dx	8.2 (2.8)	<0.01
Time×Cardiac Dx	−0.05 (0.05)	0.24
OEF
Intercept	0.56 (0.03)	<0.0001
Time, hr	0.0014 (0.0005)	0.01
Cardiac Dx	−0.07 (0.04)	0.09
Time×Cardiac Dx	0.0005 (0.0007)	0.45
BFI, 10−8 cm2/s
Intercept	2.0 (0.1)	<0.0001
Time, hr	−0.003 (0.003)	0.16
Cardiac Dx	−0.35 (0.18)	0.05
Time×Cardiac Dx	0.001 (0.003)	0.69
CMRO2,i, 10−7 ml/dl × cm2/s
Intercept	2.0 (0.2)	<0.0001
Time, hr	0.002 (0.004)	0.68
Cardiac Dx	−0.28 (0.27)	0.30
Time×Cardiac Dx	0.0006 (0.006)	0.91

For each outcome variable, the table reports the y-intercept for the linear model as well as the coefficients for the 3 variables: time after birth, cardiac diagnosis (HLHS and TGA), and an interaction term between diagnosis and time. For cardiac diagnosis, TGA was used as the reference group. The linear model for each outcome variable is y = β₀ + β₁ × Time + β₂ × Cardiac Diagnosis + β₃ × Time × Cardiac Diagnosis.