Table 1.
Baseline patient characteristics.
| Ticagrelor (n = 133) | Clopidogrel (n = 67) | p-value | |
|---|---|---|---|
| Age (years), mean SD | 62.9 ± 11.6 | 70.4 ± 11.6 | <0.001 |
| Female sex (%) | 27.0 | 31.3 | 0.616 |
| Health care card holder (%) | 54.4 | 64.2 | 0.221 |
| Annual household income (AUD) (%) | 0.229 | ||
| <40,000 | 56.8 | 71.2 | |
| 40,001–60,000 | 16.8 | 12.1 | |
| 60,001–80,000 | 6.4 | 4.5 | |
| 80,001–100,000 | 4.0 | 6.1 | |
| >100,000 | 12.0 | 6.1 | |
| Marital status (%) | 0.082 | ||
| Single | 14.5 | 3.0 | |
| Married/defacto | 54.8 | 67.2 | |
| Divorced/widowed | 30.6 | 29.9 | |
| Employed full time (%) | 28.6 | 16.4 | 0.042 |
| Body mass index (kg/m2 ), mean ± SD | 29.5 ± 6.1 | 28.7 ± 4.8 | 0.560 |
| Smoker (%) | 35.4 | 22.4 | 0.073 |
| Pre-existing ischaemic heart disease (%) | 27.6 | 40.3 | 0.077 |
| Atrial fibrillation (%) | 5.5 | 20.9 | 0.003 |
| Heart failure (%) | 11.0 | 14.9 | 0.493 |
| Asthma (%) | 11.0 | 16.4 | 0.367 |
| Chronic obstructive pulmonary disease (%) | 6.8 | 7.4 | 1.00 |
| Anaemia (%) | 1.6 | 9.0 | 0.021 |
| Number of preadmission medications, mean ± SD | 4.0 ± 3.9 | 5.5 ± 4.0 | 0.012 |
| Charlson comorbidity index | 3.5 ± 2.7 | 4.9 ± 3.0 | 0.001 |
| Diagnosis at admission (%) | 0.022 | ||
| STEMI | 45.7 | 34.3 | |
| NSTEMI | 40.9 | 34.3 | |
| Other | 13.4 | 31.4 | |
| Mean length of stay ± SD (days) | 4.3 ± 3.7 | 4.9 ± 3.4 | 0.290 |
| Medications prescribed at discharge (%) | |||
| ACE inhibitor | 68.5 | 65.7 | 0.748 |
| AT 2 receptor inhibitor | 20.5 | 16.4 | 0.567 |
| Beta blocker | 87.4 | 83.6 | 0.515 |
| Statin | 100 | 92.5 | 0.004 |
| Aspirin | 95.8 | 84.9 | 0.042 |
| Glyceryl trinitrate buccal spray/tablet | 78.7 | 68.2 | 0.117 |
| Diuretics | 15.6 | 9.0 | 0.280 |
| Mean MRCI preadmission ± SD | 12.7 ± 13.3 | 16.7 ± 13.1 | 0.049 |
| Mean MRCI post-admission ± SD | 25.2 ± 12.0 | 25.5 ± 10.3 | 0.860 |
| Mean change in MRCI ± SD | 12.6 ± 5.3 | 8.8 ± 7.2 | <0.001 |
ACE, angiotensin converting enzyme; AT, angiotensin; MRCI, medication regimen complexity index; NSTEMI, non-ST-elevation myocardial infarction; SD, standard deviation; STEMI, ST-elevation myocardial infarction.
*
observations missing for some patients.