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. 2018 Sep 17;2018:4054815. doi: 10.1155/2018/4054815

(c) Enhancing cytotoxicity

Gene Gene transfer vector Cell type Target Gene transfer efficiency Ref
miR-27a-5p miRNA Lipofection Peripheral blood NK cells Enhanced cytotoxicity N/A Regis et al. [163]
DNTβRII Retrovirus Cord blood NK cells Enhanced cytotoxicity 75.8% Yvon et al. [198]
DNTβRII Nucleofection NK-92 Enhanced cytotoxicity N/A Zhang et al. [155]
CD16 cDNA Retrovirus NK-92 Antibody-dependent cell-mediated cytotoxicity N/A Binyamin et al. [199]

GALV: gibbon ape leukemia virus. All studies present data in vivo unless otherwise stated.