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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Mater Today (Kidlington). 2018 Apr 17;21(7):703–712. doi: 10.1016/j.mattod.2018.03.002

Figure 5.

Figure 5

Using cell VECT to deliver a variety of molecules to cells. (a) Confocal microscopy showed diffuse delivery of Cy5-labeled mRNA throughout the interior of a fixed cell with nucleus staining. No Device control showed no such delivery. Scale bar 5 μm, n = 2. Images shown are representative of ~50 cell images. (b) Transfection of EGFP mRNA in K562 cells with substantial efficiency. (c) Device delivery of SmartFlare RNA microparticle probes to PC3 cells was competitive with the established method of 24 hr endocytosis. (d) Device successfully delivered SmartFlare to K562 cells which do not endocytose SmartFlares. (e) Successful delivery of 2000 kDa FITC-dextran to primary leukocytes isolated from discarded donor blood.