Table 1. . Patient characteristics.
| Charactersistics | Diabetic patients | Combination therapy | Monotherapy | p-value | Metformin | p-value | Sulfonylurea | p-value | Insulin | p-value | PPAR-γ | p-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients (n) | 123 | 56 | 67 | – | 18 | – | 18 | – | 26 | – | 5 | – |
| Median age; years (range) | 66 (29–90) | 65 (29–90) | 68 (39–84) | 0.3 | 63 (39–79) | 0.2 | 71.5 (59–84) | 0.005 | 67.5 (40–79) | 0.15 | 71 (50–77) | 0.8 |
| Median KPS (range) | 80 (40–100) | 80 (40–90) | 70 (40–100) | 0.04 | 70 (50–100) | 0.3 | 60 (40–90) | 0.2 | 70 (40–100) | 0.9 | 80 (50–90) | 0.7 |
| Men; n (%) | 86 (70) | 41 (73) | 45 (67) | 0.5 | 13 (72) | 0.6 | 13 (72) | 0.6 | 12 (46) | – | 0 | 0.2† |
| Women; n (%) | 37 (30) | 15 (27) | 22 (33) | – | 5 (28) | – | 5 (28) | – | 14 (53) | 0.07 | 5 (100) | 0.3† |
| DM2; n (%) | 89 (72) | 41 (73) | 48 (72) | 0.9 | 14 (78) | 0.5 | 15 (83) | 0.2 | 14 (54) | 0.01 | 5 (100) | – |
| Steroid use: Data available (n) ▪ Dependent; n (%) ▪ Weaned; n (%) ▪ Data missing; n (%) |
120 102 (83) 18 (15) 3 (2) |
56 49 (87.5) 7 (12.5) 0 |
64 53 (79) 11 (16) 3 (5) |
0.5 |
17 14 (78) 3 (17) 1 (6) |
1.0† |
18 16 (89) 2 (11) 0 |
0.7† |
24 19 (73) 5 (19) 2 (8) |
0.7† |
5 4 (80) 1 (20) 0 |
1.0† |
| Gross total resection; n (%) | 23 (19) | 15 (27) | 8 (12) | 0.04 | 4 (22) | 0.2† | 1 (6) | 0.4† | 2 (8) | 0.5† | 1 (20) | 0.5† |
| Subtotal resection; n (%) | 71 (58) | 31 (55) | 40 (60) | 0.6 | 8 (44) | 0.13 | 13 (72) | 0.2 | 17 (65) | 0.5 | 2 (40) | 0.4† |
| Biopsy only; n (%) | 29 (23) | 10 (18) | 19 (28) | 0.2 | 6 (33) | 0.6 | 4 (22) | 0.6† | 7 (27) | 0.8 | 2 (40) | 0.6† |
| Chemotherapy; n (%) | 79 (64) | 38 (68) | 41 (61) | 0.4 | 13 (72) | 0.4† | 10 (56) | 0.6 | 16 (62) | 0.9 | 2 (40) | 0.4† |
| Radiation; n (%) | 104 (85) | 50 (89) | 54 (81) | 0.2 | 16 (89) | 0.5† | 15 (83) | 0.7 | 20 (77) | 0.6 | 3 (60) | 0.2† |
| Chemoradiation; n (%) | 75 (61) | 37 (66) | 38 (57) | 0.3 | 13 (72) | 0.2† | 9 (50) | 0.5 | 15 (58) | 0.9 | 1 (20) | 0.2† |
| HbA1c: ▪ Data available (n) ▪ Median ▪ Range ▪ Mean |
68 7.65 5.4–13.6 7.88 |
34 7.4 5.4–11 7.8 |
34 7.95 5.5–13.6 8 |
0.6 |
10 7.7 5.5–8.5 7.25 |
0.15 |
8 8.2 5.6–13.6 8.3 |
0.6 |
16 7.8 5.9–12.9 8.3 |
0.4 |
0 – – – |
– |
| Median glucose (mg/dl): ▪ Data available (n) ▪ Median ▪ Range ▪ Mean |
119 198.5 98.5–321.1 196 |
54 204 98.5–321.5 203 |
65 190 111–295 191 |
0.09 |
17 182 111–255.5 178 |
0.1 |
17 193.5 134–268 198 |
0.3 |
26 189 132–295 195 |
0.5 |
5 188 170–205.5 188.5 |
0.9 |
†Fisher's exact test; all other comparisons used the Student's t-test.
DM2: Type 2 diabetes mellitus; KPS: Karnofsky Performance Score.