Figure 2.

Primary end point: neutrophil phagocytosis at day 2. Neutrophils were isolated from whole blood on day 2 as described in the Methods. Neutrophils were incubated with serum-opsonised zymosan particles for 30 min and the proportion ingesting two or more particles was determined at light microscopy. n=36 (one patient in the GM-CSF group died before day 2, another was withdrawn from the study because of thrombocytosis). Data were analysed on an intention-to-treat basis by two-sample t-test and are shown as individual points. ns, p>0.05. GM-CSF, granulocyte-macrophage colony-stimulating factor.