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. 2018 Apr 29;89(10):1016–1023. doi: 10.1136/jnnp-2017-317887

Table 2.

Correlations between metabolic index and patient information collected at the time of metabolic assessment

Characteristic at time of metabolic assessment Pearson
correlation, r
P values*
Demographics
  Age (years) −0.19 (−0.4 to 0.07) 0.16
  BMI 0.16 (−0.11 to 0.40) 0.24
  Fat mass (%) 0.11 (−0.15 to 0.36) 0.39
  Fat-free mass (kg) 0.02 (−0.24 to 0.28) 0.87
  Time since onset (months†) 0.03 (−0.23 to 0.29) 0.81
  Diagnostic delay (months) −0.05 (−0.22 to 0.30) 0.74
Clinical scores
  ALSFRS-R −0.08 (−0.33 to 0.18) 0.56
  FVC, % of predicted 0.16 (−0.20 to 0.49) 0.37
  UMN score 0.05 (−0.22 to 0.32) 0.69
  LMN score† 0.47 (0.23 to 0.65) <0.01
Cognitive indices
  ECAS total score (n=24) 0.20 (−0.22 to 0.56) 0.34
  ACE III total score (n=38) 0.41 (0.10 to 0.64) 0.01

Data presented as mean (range).

*P value is based on Pearson correlation.

†Log-transformed value.

ACE III, Addenbrooke’s Cognitive Examination III, data corrected for items administered; ALSFRS-R, ALS Functional Rating Scale-Revised; BMI, body mass index; ECAS, Edinburgh Cognitive and Behavioural ALS Screen; FVC, forced vital capacity; LMN, lower motor neuron; UMN, upper motor neuron.