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. 2018 Jul 6;17(10):2005–2017. doi: 10.1074/mcp.RA118.000882

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© 2018 Wang et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Fig. 2. — Proteomic analysis of CD38(−) and CD38(+) cells. A, Venn diagram showed that proteomic data were highly reproducible. B, Volcano plots showed significantly changed proteins (labeled in blue) between CD38(+) and CD38(−) A549 cells with fold-change > 2 or < 0.5 and adjusted p value < 0.05 from t test statistics. C, Pearson correlation diagram embedded with a histogram revealed that protein fold-changes in our proteomic data showed normal distributions. High Pearson correlation coefficient indicates high correlation of protein fold-changes between three independent experiments. D, Functional classification of downregulated proteins between CD38(−) and CD38(+) A549 cells by PANTHER (http://www.pantherdb.org). E, SILAC ratios for NAD(P)-dependent enzymes.