Figure 3.

NMR structure of TF^PPD in complex with MBP. A, superimposition of 20 structures of TF^PPD in complex with MBP 238–266. For MBP, only the converged region, Asn²⁵³–Ser²⁵⁹, is shown for clarity. TF^PPD and MBP are shown in green and pink ribbons, respectively. B and D, the lowest-energy structure of MBP–TF^PPD complex. TF^PPD is shown as a solvent-exposed surface to which the hydrophobicity (B) or the conservation of the amino acid residues (D) is mapped. MBP is shown as pink ribbons. The MBP residues that directly interact with TF^PPD are drawn in a ball-and-stick representation. C, close-up view of the lowest-energy structure of MBP–TF^PPD complex. TF^PPD and MBP are shown as green and pink ribbons, respectively. The residues of TF^PPD and MBP involved in the interaction are drawn in a ball-and-stick representation and colored green and pink, respectively.