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A, the lyase domain of Pol β interacts with DNA in the ternary structure. Lys-35 and Lys-68 interact with the 5′-phosphate group on the downstream DNA. His-34 stacks with the nucleobase at the T+1 position of the template DNA. B, interactions between the lyase domain (yellow) and fingers domain (light blue) of Pol β in the ternary structure. The PDB code for structure is 2FMS (47).
