Table 4.
Causes of death within 5 years after HTX
| Parameter | FEV1/FVC <0.70 (n=63) | FEV1/FVC ≥0.70 (n=196) | Difference | 95% CI |
|---|---|---|---|---|
| Transplant failure, n (%) | 11 (17.5%) | 10 (5.1%) | 12.4% | 2.6%, 22.2% |
| Acute rejection, n (%) | 0 (0.0%) | 2 (1.0%) | 1.0% | −0.4%, 2.4% |
| Infection/sepsis, n (%) | 20 (31.7%) | 25 (12.8%) | 18.9% | 6.5%, 31.3% |
| Pulmonary infection, n (%) | 15 (23.8%) | 19 (9.7%) | 14.1% | 2.8%, 25.4% |
| Abdominal infection, n (%) | 5 (7.9%) | 6 (3.1%) | 4.8% | −2.3%, 11.9% |
| Malignancy, n (%) | 3 (4.8%) | 2 (1.0%) | 3.8% | −1.6%, 9.2% |
| Thromboembolic event/bleeding, n (%) | 6 (9.5%) | 2 (1.0%) | 8.5% | 1.1%, 15.9% |
| All causes, n (%) | 40 (63.5%) | 41 (20.9%) | 42.6% | 29.4%, 55.8% |
Abbreviations: FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; FEV1/FCV, Tiffeneau index; HTX, heart transplantation.