Figure 9.

Downregulation of LY333531-induced PGP9.5 and VEGF expression in the spinal cord and the DRG. (A, B) Expression of PGP9.5 and VEGF in the spinal cord after LY333531 treatment was determined by densitometric analysis on Western blots using GAPDH as the internal control. Compared with the control and DMSO group, *P < 0.05, **P < 0.01, ***P < 0.001; n=5 for each group. (C, D) Expression of PGP9.5 and VEGF in the DRG after LY333531 treatment was determined by densitometric analysis on Western blots using GAPDH as the internal control. Compared with the control group, LY group, and DMSO group, *P < 0.05, **P < 0.01; n=5 for each group.

Abbreviations: SMIR, skin/muscle incision and retraction; DRG, dorsal root ganglion; VEGF, vascular endothelial growth factor; GAPDH, glyceraldehyde phosphate dehydrogenase; LY, LY333531; PGP, protein gene product.