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. 2018 Sep 27;13:5849–5863. doi: 10.2147/IJN.S177109

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© 2018 Lu et al. This work is published and licensed by Dove Medical Press Limited

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Biocompatibility and biodegradability of nano-adhesives.

Notes: The cytotoxicity of MSNs and Ag-MSNs against (A) HaCaT cells and (B) NIH-3T3 cells at different levels of concentration after 24 hours. (C) Cumulative degradation profile of MSNs and Ag-MSNs under 10 mM GSH-containing SBF for 96 hours. These data represent three separate experiments and are presented as mean values±SD. *P<0.05 vs control group. TEM images of (D) MSNs and (E) Ag-MSNs after 48 hours of incubation in SBF containing 10 mM GSH; the scale bars represent 50 nm.

Abbreviations: Ag-MSNs, nanosilver-decorated mesoporous silica nanoparticles; CON, control; GSH, glutathione; MSNs, mesoporous silica nanoparticles; SBF, simulated body fluid; TEM, transmission electron microscope.