Table 3. Five-year relative survival ratios (RSRs) and 5-year excess hazard ratios (EHRs) in relation to high-risk human papillomavirus (hrHPV) status in the 2 main histological types of invasive cervical cancer.
Histological type and hrHPV status | Cases (n = 2,635) | Deaths (n = 1,021) | 5-year RSR (95% CI) | 5-year EHR (95% CI) | |
---|---|---|---|---|---|
Crude | Adjusted* | ||||
SCC, hrHPV− | 374 | 190 | 0.59 (0.53–0.64) | Ref | Ref |
SCC, hrHPV+ | 1,735 | 665 | 0.73 (0.70–0.75) | 0.56 (0.46–0.68) | 0.68 (0.56–0.82) |
AC, hrHPV− | 116 | 81 | 0.45 (0.35–0.55) | 1.48 (1.09–2.01) | 1.44 (1.07–1.97) |
AC, hrHPV+ | 410 | 85 | 0.87 (0.83–0.90) | 0.23 (0.17–0.33) | 0.61 (0.43–0.87) |
Adenosquamous cell carcinoma (n = 119) and other rare carcinomas (n = 91) are not included in this analysis.
*EHRs were adjusted for age at cancer diagnosis as a spline term with 5 degrees of freedom, time since cancer diagnosis in 1-year bands, International Federation of Gynecology and Obstetrics (FIGO) stage, and education.
AC, adenocarcinoma; SCC, squamous cell carcinoma.