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. 2018 Oct 1;13(10):e0204421. doi: 10.1371/journal.pone.0204421

Table 2. Comparisons of morbidities between compliant and non-compliant groups.

Compliant
N = 2003
Non-compliant
N = 1060
P Value
RDS 1571 (78.4) 756 (71.3) 0.000
Air leak 82 (4.1) 25 (2.4) 0.013
Pulmonary haemorrhage 92 (4.6) 39 (3.7) 0.260
Pulmonary hypertension 96 (4.8) 46 (4.3) 0.589
PDA medication 739 (36.9) 362 (34.2) 0.133
PDA ligation 269 (12.9) 111 (10.5) 0.048
BPD (≥ moderate) 622 (31.2) 292 (27.9) 0.067
IVH (≥ grade 2) 279 (13.9) 132 (12.5) 0.266
Post-haemorrhagic hydrocephalus 68 (24.4) 39 (29.5) 0.280
PVL 154 (7.7) 105 (10.0) 0.034
NEC (≥ stage 2) 88 (4.4) 47 (4.4) 1.000
Sepsis 395 (19.7) 212 (20.0) 0.849
ROP (≥ stage 2) 482 (24.7) 201 (20.3) 0.007
ROP operation 213 (17.2) 73 (11.8) 0.002
Abnormal hearing test 296 (16.3) 108 (12.0) 0.003
Congenital anomaly 59 (2.9) 21 (2.0) 0.122
Duration of invasive ventilator use, d 16.08 [25.18] 14.18 [25.99] 0.049
Duration of supplemental oxygen use, d 9.51 [14.55] 8.27 [14.96] 0.028

Data are expressed as number of patient (%) or mean [standard deviation]. RDS, respiratory distress syndrome; PDA, patent ductus arteriosus; BPD, bronchopulmonary dysplasia; IVH, intraventricular haemorrhage; PVL, periventricular leukomalacia; NEC, necrotizing enterocolitis; ROP, retinopathy of prematurity; d, days.