Fig 2. ZLE ameliorates liver histology of S. mansoni infected CD-1 Swiss mice stained with hematoxylin and eosin, Sirius red or Masson's trichrome (Original magnification 400×).

Images representative liver histology of male CD-1 Swiss mice infected with 70±5 S. mansoni cercariae for 46 days receiving saline (healthy control), vehicle (infected mice received saline), PZQ (500 mg/kg PZQ for 2 successive days) and ZLE 200 and 400 mg/kg for 10 days. Yellow star indicate infiltrated leukocytes around granulomatous lesions and red arrow indicate schistosome eggs.