Fig 9. Ameliorative effects of the administration of Ziziphus spina-christi leaf extract (ZLE) on the mRNA level of apoptosis genes (Bcl-2, an anti-apoptotic gene; Bax, a pro-apoptotic gene) in the liver of CD-1 Swiss mice infected with S. mansoni.

After 56 days, liver homogenates were prepared to assayed Bcl-2 (A) and Bax (B) genes expression using RT-PCR method. Results (mean ± SD of three independent assays) were normalized to the GAPDH mRNA level and are shown as fold induction relative to the mRNA level in the control. ^ap<0.05, significant change with respect to the Control group; ^bp<0.05, significant change with respect to the Infected group using Duncan's post hoc test.