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. 2018 Oct 1;13(10):e0204924. doi: 10.1371/journal.pone.0204924

Fig 1. Expression of IFN stimulated genes (ISGs) in muscle in response to pcDNA3.3 and pSAV measured by microarray analysis.

Fig 1

The ISGs include the main antiviral genes, interferon regulatory factors (IRFs), virus RNA sensors and tripartite motif-containing proteins (TRIMS). Groups of fish (N = 4) were injected with PBS, pcDNA3.3 and pSAV. RNA was isolated from muscle at the injection site 7 days post injection. Numbers represent fold changes compared to the PBS group. Symbols $ and * denote significant difference (p ≤ 0.05) between PBS and plasmid groups, and between pcDNA3.3 and pSAV groups, respectively.