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. 2018 Oct 1;13(10):e0204860. doi: 10.1371/journal.pone.0204860

Fig 1. MuSCs of aged muscles showed upregulation of mmu-miR-155-5p and differentiating phenotype.

Fig 1

(A) FACS sorting of CD11bnegative(neg)/ CD31negative/ CD45negative/ITGA7positive/CD29positive fractions including MuSCs from young and aged muscles. (B) relative cell numbers of the MuSC in aged muscles to that of young mice (left). Right figure shows relative expression level of mmu-miR-155-5p in the MuSCs of aged muscles (N = 6 each). Asterisk indicates significant difference at P < 0.05. (C) gene expressions of undifferentiated (Pax7 and Notch1) and differentiating markers (Mrf4, MyoD, and Myogenin) in the young and the aged MuSCs (N = 6 each).