Table 3.

Nanoparticle-based delivery systems, including cell lines/animal models used for cervical cancer therapy.

S. No.	Drug	Type/composition of nanoparticles	Cell lines/animal models/neoplasm	References
1.	Docetaxel	Poly(ɛ-caprolactoneco-lactide)-D-α-tocopheryl polyethylene glycol succinate nanoparticles	Cervical cancer cells	[50]
2.	Docetaxel	Colic acid-PLGA-b-Vitamin E TPGS copolymer	–	[51]
3.	Cisplatin	Folic acid-conjugated gelatin nanoparticles	–	[52]
4.	–	Phenanthridinium (oligonucleotide intercalator)-functionalized mesoporous silica nanoparticles	HeLa cells	[53]
5.	Bleomycin sulfate	Nanostructured lipid particles	Cervical cancer cells	[54]
6.	Doxorubicin	Polynorbonene-cholesterol/poly(ethylene glycol)	–	[55]
7.	Doxorubicin	Mesoporous silica nanoparticles	HeLa cells	[56]
8.	Docetaxel	D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-lactide) nanoparticles	Xenograft BALB/c nude mice tumor model	[57]
9.	Doxorubicin	Cyclodextrin-containing pH-sensitive poly(2-(dimethylamino) ethyl methacrylate) star polymer nanoparticles	–	[58]
10.	Paclitaxel	Poly(γ-glutamic acid-maleimide-co-l-lactide)-1,2-dipalmitoylsn-glycero-3-phosphoethanolamine (γ-PGA-MAL-PLADPPE) copolymer-based nanoparticles	–	[59]
11.	Docetaxel	Poly(lactide-co-glycolide) and pluronic F68	Cervical cancer cells	[60]
12.	Methotrexate and 5-flurouracil	Double hydroxide nanoparticles	–	[61]
13.	Hexylaminolevulinate (HAL)	Bioadhesive pellets of Carbopol 934	Cervical cancer cells	[62]
14.	Paclitaxel and curcumin	Polyethylene gycol phosphatidyl ethanolamine (PEG-PE)-based polymeric micelles	Multidrug-resistant ovarian cancer cells	[63]
15.	Doxorubicin	Folate (FA)-modified carboxymethyl chitosan (FCC)	HeLa cells	[64,65]
16.	Paclitaxel	Cremophor EL-free nanoparticles	HeLa cells	[66]
17.	Docetaxel	PLGA-TPGS, glycolide and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) nanoparticles	HeLa cells	[67]
18.	Paclitaxel	PEG/PCL biotin-conjugated nanoparticles	Normal human fibroblasts and HeLa cells	[68]
19.	Paclitaxel	Paclitaxel-loaded nanoparticles	MCF-7 and HeLa cells	[69]
20.	Doxorubicin	Oleoyl-chitosan (OCH) nanoparticles	HeLa cells	[70]
21.	Docetaxel	D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) nanoparticles	HeLa cells	[71]
22.	Docetaxel	D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-lactide) nanoparticles	Xenograft BALB/c nude mice tumor model	[72]
23.	Silver nanoparticles	Polyethylene glycol	HeLa and CaSki cells	[73]