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. 2018 Sep 25;2(10):1247–1258. doi: 10.1002/hep4.1240

Figure 4.

Figure 4

The HCV E2 glycoprotein may upregulate CEACAM1 expression on Huh7.5.1/JFH‐1 cells. (A) CEACAM1 expression on untreated and treated SGR cells was analyzed by flow cytometry (means ± SD, n = 4). (B) CEACAM1 expression on untreated and treated FGR cells was measured by flow cytometry (means ± SD, n = 4). (C) We overexpressed the HCV core protein, E1 glycoprotein, and E2 glycoprotein in Huh7.5.1 cells using a lentiviral vector system. CEACAM1 expression on these cells was evaluated by flow cytometry (means ± SD, n = 4). The shaded area represents the isotype control, the solid line represents mock‐infected cells, and the dotted line represents overexpressing cells. * P < 0.05.