Table 2.
Independent Predictors of Overall and CV Mortality in NAFLD, NHANES III (1988‐1994)
Covariate | Overall Mortality aHR (95% CI) | P | Cardiovascular Mortality aHR (95% CI) | P | |
Group by medication use | 0.1512 | 0.409 | |||
No medication use | Reference | Reference | |||
Statin use | 0.95 (0.37‐2.44) | 0.9143 | 1.20 (0.26‐5.54) | 0.8092 | |
Other LLA use | 1.43 (0.99‐2.07) | 0.0544 | 1.63 (0.70‐3.76) | 0.2488 | |
Age, years | < 0.0001 | < 0.0001 | |||
20‐44 | Reference | Reference | |||
45‐54 | 2.74 (1.68‐4.48) | 0.0001 | 2.81 (1.49‐5.29) | 0.0019 | |
55‐64 | 7.31 (4.92‐10.85) | < 0.0001 | 8.85 (3.61‐21.68) | < 0.0001 | |
65‐74 | 15.58 (10.72‐22.63) | < 0.0001 | 21.49 (11.04‐41.84) | < 0.0001 | |
Male | 1.20 (0.99‐1.47) | 0.0681 | 1.48 (0.86‐2.57) | 0.1557 | |
Race | 0.0011 | 0.0882 | |||
non‐Hispanic white | Reference | Reference | |||
non‐Hispanic black | 1.11 (0.92‐1.35) | 0.2700 | 0.93 (0.56‐1.56) | 0.7863 | |
Mexican American | 0.91 (0.72‐1.16) | 0.4368 | 0.85 (0.55‐1.32) | 0.4691 | |
Other | 0.40 (0.25‐0.65) | 0.0004 | 0.14 (0.03‐0.65) | 0.0133 | |
Active smoker | 1.94 (1.48‐2.55) | < 0.0001 | 2.65 (1.76‐3.97) | < 0.0001 | |
Obese | 0.96 (0.77‐1.20) | 0.7112 | 1.03 (0.64‐1.66) | 0.9030 | |
DM | 1.79 (1.40‐2.30) | < 0.0001 | 1.89 (1.08‐3.30) | 0.0260 | |
HL | 1.10 (0.84‐1.45) | 0.4687 | 1.23 (0.78‐1.94) | 0.3631 | |
HTN | 1.13 (0.84‐1.54) | 0.4121 | 1.17 (0.75‐1.82) | 0.4834 | |
CKD | 1.89 (1.48‐2.41) | < 0.0001 | 1.82 (0.92‐3.62) | 0.0860 | |
History of cancer | 1.21 (0.87‐1.67) | 0.2502 | 0.75 (0.45‐1.24) | 0.2578 | |
History of CVD | 2.03 (1.57‐2.63) | < 0.0001 | 3.69 (2.23‐6.08) | < 0.0001 |