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BMP7 heterozygous knockout mice exhibit decreased striatal TH-immunoreactivity following MA exposure. (A) MA administration suppressed THir in +/+ (1 vs. 2) and +/− mice (3 vs. 4). Scale bar=2 mm. (B) THir fiber density analysis indicated that MA suppressed THir in +/+ and +/− mice. There is a marginal difference in striatal THir (P=0.086) between +/+ and +/− mice after MA injection.
