Table 2.

DOPAC, DA and DOPAC/DA ratio in B6, CBA and congenic mice

Strain/line	Time (n)	DOPAC (pg/eye)	Dopamine (pg/eye)	DOPAC/DA ratio
B6	CT06 (4)	243.5 ± 44.7	2,041.0 ± 66.4	0.122 ± 0.0253
	CT18-20 (4)	282.7 ± 43.7	1,719.4 ± 80.1 (*)	0.165 ± 0.0256
CBA	CT06 (5)	790.5 ± 20.2 (†††)	2,091.6 ± 40.1	0.379 ± 0.0121 (†††)
	CT18-20 (5)	484.1 ± 18.7 (***, †††)	1,855.1 ± 32.1 (**)	0.261 ± 0.00996 (***, †††)
B6 congenic	CT06 (6)	352.6 ± 8.55 (†, ###)	1,236.6 ± 32.6 (†††, ###)	0.286 ± 0.00883 (†††, ##)
	CT18-20 (6)	311.8 ± 3.92 (***, ###)	1,200.9 ± 17.4 (*, †††, ###)	0.269 ± 0.00259 (*, †††)
ANOVA	CT06	F(2,12)=140.2 (P=4.8e-9)	F(2,12)=128.4 (P=7.9e-9)	F(2,12)=68.5 (P=2.7e-7)
	CT18-20	F(2,12)=22.7 (P=8.4e-5)	F(2,12)=73.7 (P=1.8e-7)	F(2,12)=16.1 (P=4.0e-4)

Data are mean ± SEM from n animals. Subjective day/subjective night difference was tested within each genotype using 2-tailed unpaired Student’s t-test:

^*P<0.05,

^**P<0.01,

^***P<0.001.

Differences between daytime values or between nighttime values were tested between genotypes using one-way ANOVA followed by Tukey post-hoc analysis.

^†P<0.05,

^†††P<0.001 (compared to B6),

^##P<0.01,

^###P<0.001 (compared to CBA).