Table 1.

Differences in descriptors between active and inactive Mtb compounds - Training set (mean±SEM) 100 nM.

Number	Class	AlogP	MW	Number of Aromatic Rings	Hydrogen Bond Acceptors	Hydrogen Bond Donors	Number of rings	Rotatable Bonds	FPSA
18241	inactive	3.80 ± 0.01	378.59 ± 1.02	2.62 ± 0.008	4.51 ± 0.02	1.10 ± 0.009	3.48 ± 0.01	5.35 ± 0.04	0.23 ± 0.00072
645	active	3.50 ± 0.074	427.54 ± 5.43	2.10 ± 0.044	6.04 ± 0.10	1.43 ± 0.05	3.39 ± 0.05	6.75 ± 0.19	0.25 ± 0.0038
	2 tailed T test p value	<.0001	<.0001	<.0001	<.0001	<.0001	0.09	<.0001	<.0001