Table 2.

Differences in descriptors between active and inactive Mtb compounds - Training set (mean±SEM) 1 µM.

Number	Class	AlogP	MW	Number of Aromatic Rings	Hydrogen Bond Acceptors	Hydrogen Bond Donors	Number of rings	Rotatable Bonds	FPSA
16535	inactive	3.82 ± 0.01	377.39 ± 1.07	2.62 ± 0.009	4.47 ± 0.02	1.10 ± 0.01	3.47 ± 0.01	5.35 ± 0.04	0.23 ± 0.00075
2351	active	3.63 ± 0.04	400.24 ± 2.84	2.51 ± 0.023	5.17 ± 0.05	1.16 ± 0.03	3.53 ± 0.03	5.72 ± 0.10	0.24 ± 0.002
	2 tailed T test p value	<.0001	<.0001	<.0001	<.0001	0.04	0.07	0.0006	<.0001