Table 3.

Differences in descriptors between active and inactive Mtb compounds - Training set (mean±SEM) 10 µM.

Number	Class	AlogP	MW	Number of Aromatic Rings	Hydrogen Bond Acceptors	Hydrogen Bond Donors	Number of rings	Rotatable Bonds	FPSA
11124	inactive	3.79 ± 0.02	371.02 ± 1.31	2.56 ± 0.011	4.38 ± 0.02	1.12 ± 0.01	3.41 ± 0.01	5.29 ± 0.05	0.22 ± 0.00092
7762	active	3.79 ± 0.02	393.50 ± 1.56	2.66 ± 0.012	4.82 ± 0.03	1.09 ± 0.01	3.58 ± 0.01	5.54 ± 0.05	0.23 ± 0.00110
	2 tailed T test p value	0.86	<.0001	<.0001	<.0001	0.13	<.0001	0.0006	<.0001