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. 2018 Jul;1859(7):482–490. doi: 10.1016/j.bbabio.2018.03.014

Fig. 1.

Fig. 1

Quinolone and quinolinyl pyrimidine NDH-2 inhibitors described in this study. 1) 2-Heptyl-4-hydroxyquinoline-N-oxide. 2) 1-1-Hydroxy-2-dodecyl-4(1H)quinolone. 3) Bisaryl quinolone (PfNDH-2 inhibitor) [13] 4) RY-552 (PfNDH-2 inhibitor) [9] 5) Quinolinyl pyrimidine (Mtb NDH-2 inhibitor) [11] Bulky bisaryl and phenyl pyrimidine groups are enclosed in red boxes, and a 4-fluorophenyl group is enclosed in a blue box.