Fig. 2. Graphs illustrating the effect of diluted bee venom (dBV) treatment on leukocyte accumulation in pleural exudate. Intrapleural injection of carrageenan (CA) markedly induced the accumulation of leukocytes into the CA-injected pleural cavity compared to that of sham animals (Sham). The 0.8 mg/kg dBV apipuncture of LU-5 (CA + BV-A 0.8) significantly inhibited the accumulation of leukocytes in pleural exudate compared with that of vehicle-treated CA mouse (CA + Veh) (p < 0.01). However, 0.08 mg/kg dBV apipuncture of LU-5 (CA + BV-A 0.08) or 0.8 mg/kg dBV apipuncture of non-acupoint (CA + BV-NA 0.8) did not affect the number of leukocytes in pleural exudate compared to that of vehicle-treated CA group (CA + Veh). ^***p < 0.001 compared to that of sham animals.