Fig. 5. Graphs and photomicrographs illustrating the effect of diluted bee venom (dBV) treatment on Fos expression in the ipsilateral (Ipsi) and contralateral (Contra) hypothalamic paraventricular nucleus (PVN). (A) Two hours after 0.8 mg/kg dBV stimulation of the LU-5 acupoint, the number of Fos-immunoreactive (Fos-ir) neurons significantly increased in the contralateral side of PVN in the dBV-treated group (BV-A 0.8) compared to that of the vehicle-treated group (Veh-A) (p < 0.05). (B) Representative PVN sections demonstrating the typical pattern of Fos-ir in the groups. Scale bars = 100 µm.
