Table 2.
Risk estimates for leukocyte relative telomere length and GCA.
| Variables | Relative Telomere Length | Controls, N (%) | Cases, N (%) | OR (95% CI)a | P valuea |
|---|---|---|---|---|---|
| Overall telomere length | |||||
| Long | ≥1.180 | 255 (50.00) | 201 (38.36) | 1.00 | |
| Short | <1.180 | 255 (50.00) | 323 (61.64) | 1.71 (1.31–2.24) | 9.05 × 10−5 |
| Quartile | |||||
| 75–100% | ≥1.448 | 127 (24.90) | 90 (17.18) | 1.00 | |
| 50–75% | 1.180–1.447 | 128 (25.10) | 111 (21.18) | 1.49 (1.00–2.22) | 0.052 |
| 25–50% | 0.898–1.179 | 128 (25.10) | 160 (30.53) | 2.07 (1.40–3.04) | 2.33 × 10−4 |
| 0–25% | <0.898 | 127 (24.90) | 163 (31.11) | 2.18 (1.47–3.22) | 9.90 × 10−5 |
| P trend b | 3.38 × 10−5 | ||||
Abbreviations: GCA, gastric cardia adenocarcinoma; OR, odds ratio; CI, confidence interval; SD, standard deviation.
aData were calculated by logistic regression with adjustments for age, sex, smoking and drinking status.
bTest for trend of odds was two-sided and based on likelihood ratio test assuming a multiplicative model.