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. 2018 Oct 2;7(9):77. doi: 10.1038/s41389-018-0088-9

Fig. 1. FIBP is a prognostic indicator of CRC progression and is expressed at higher levels in chemoresistant CRC tissues.

Fig. 1

a The hazard risk (HR) distribution of 56 genes with high expression and association with poor prognosis based on TCGA raw data from cBioPortal. The filtering criteria are p < 0.05 and HR > 0. b Venn diagram showing that FIBP, HSFY1, and PPM1K are simultaneously present in both the set of genes with a high HR and the set of genes downregulated by curcumin. c Expression of FIBP was higher in CRC specimens with chemoresistance (CR) than in chemosensitive tissue. n = 10 for the CRC group, and n = 6 for the CRC with CR group. d Representative immunochemistry staining results in tumors with/without chemoresistance (magnification, ×200). e Kaplan–Meier survival curves according to FIBP levels. *p < 0.05 CRC vs. CRC with CR