Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 25;9:2173. doi: 10.3389/fimmu.2018.02173

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Marschner, Mulay, Steiger, Anguiano, Zhao, Boor, Rahimi, Inforzato, Garlanda, Mantovani and Anders.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Recombinant human PTX3 inhibits supersaturation-induced CaOx crystal aggregation. (A) Calcium oxalate crystals were generated in chemico in the presence of increasing concentrations of rhPTX3 and crystal size was measured microscopically 24 h later. (B) The effect of 1 μM rhPTX3 on microscopically measured calcium oxalate crystal size was compared to equimolar bovine serum albumin (BSA) and PBS. (C,D) Calcium oxalate crystals generated in the presence of 1 μM BSA or equimolar rhPTX3 were compared for their forward scatter (FSC) signal intensity by flow cytometry and displayed for (C) relative frequency of FSC and (D) overall FSC intensity. Data are from three independent experiments and represent means ± SEM in (A). n.s., not significant; *p < 0.05, ***p < 0.001 between groups as indicated.