Mean (SEM) for MMTT analyte time profiles by GT population. After baseline samples, the meal was administered at time 0. Glucose, insulin and c-peptide measurements were made out until 240 min postmeal consumption. GLP-1, glucagon, PYY, and GIP were assayed for all subjects until 120 min postmeal after it was determined in a subset of subjects that values stabilized or returned to baseline by 120 min postmeal. GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide-1; GT, glucose tolerance; MMTT, mixed meal tolerance test; PYY; peptide YY; SEM, standard error of mean.