REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
2G12, PG9, PG16, b12, 447-52D, 5F3, 4E10, 2F5, F240, 4B3	Polymun Scientific	N/A
48d, E51, 10-1074, 2191, 2219, 3074, 3869, 35O22, 98-6D, 167-D	NIH AIDS Reagent Program	N/A
39F, 19b, 3BC176, 3BC315, b6, F105, PGT121, PGT135, PGT145, PGT151, VRC01	Produced in house	N/A
17b, 7B2	James Robinson	N/A
Mouse anti-human c-Myc IgG1 (9E10)	Produced in house	N/A
Goat anti-rabbit IgG Fc	Jackson ImmunoResearch	Cat# 111-005-046; RRID: AB_2337917
Rabbit IgG	Bio-Rad	Cat# PRABP01; RRID: AB_321631
Mouse anti-rabbit IgG biotinylated (Clone RG-96)	Sigma	Cat# B5283; RRID: AB_258574
Goat anti-guinea pig IgG F(ab’)2	Jackson ImmunoResearch	Cat# 106-005-006; RRID: AB_2337395
Guinea pig IgG	Jackson ImmunoResearch	Cat# 006-000-003; RRID: AB_2337022
Donkey anti-guinea pig IgG (H+L) biotinylated	Sigma	Cat# 3700388
F(ab’)2-goat anti-human IgG Fc PE	Invitrogen	Cat# H10104; RRID: AB_1500728
Goat anti-human IgG Fc biotinylated	Southern Biotech	Cat# 2048-08
Bacterial and Virus Strains
Pseudotyped HIV-1: MW965.26, ConM, ConS, MN, SF162, TV1.29	Produced in house	N/A
Chemicals, Peptides, and Recombinant Proteins
Soluble CD4 D1D2 His-tagged	Produced in house	N/A
ConSOSL.UFO.664 gp140	This paper	N/A
ConSOSL.UFO.664 Myc-His tagged	This paper	N/A
ConSOSL.UFO V3 cys-cyclised peptide	Synthesized by JPT	N/A
MN.3 V3 scrambled linear peptide	Synthesized by JPT	N/A
Polyethyleneimine “MAX” (MW 40,000)	Polysciences	Cat# 24765
Poly-HRP 40	Fitzgerald	Cat# 65RMS104PHRP
Casein buffer	ThermoFisher Scientific	Cat# 37528
Collagen I, rat tail	Invitrogen	Cat# A1048301
Recombinant human bFGF	GIBCO	Cat# 13256029
Luminata Crescendo ELISA HRP substrate	Merck Millipore	ELLUR0200
Experimental Models: Cell Lines
HEK293T/17 cells	ATCC	Cat# CRL-11268; RRID: CVCL_1926
MYC 1-9E10.2 [9E10] hybridoma	ATCC	Cat# CRL-1729; RRID: CVCL_G671
Human skeletal muscle primary cells	DV Biologics	Cat# AM003-F-DMD
TZM-bl cells	NIH AIDS Reagent Program	Cat# 8129; RRID: CVCL_B478
Experimental Models: Organisms/Strains
Female New Zealand white rabbits	Charles River	Crl:KBL(NZW) strain code 052
Female Dunkin-Hartley guinea pigs	Charles River	Crl:HA strain code 051
Female BALB/c mice	Charles River	Balb/cAnNCrl strain code 028
Recombinant DNA
pSG3ΔEnv	NIH AIDS Reagent Program	Cat# 11051
Software and Algorithms
Flowjo v10	Treestar	https://www.flowjo.com/
Prism v7	GraphPad Software	https://www.graphpad.com/scientific-software/prism/
Chromlab v4	BioRad	https://www.bio-rad.com/en-uk/product/chromlab-software?ID=MFCVPXIVK
Microsoft Office	Microsoft	https://www.office.com/
Driftscope v2.8	Waters	http://www.waters.info/waters/library.htm?lid=10103987&cid=511436
MassLynx v4.1	Waters	http://www.waters.com/waters/en_GB/MassLynx-Mass-Spectrometry-Software-/nav.htm?cid=513164&locale=en_GB
Byonic v2.7	Protein Metrics	https://www.proteinmetrics.com/products/byonic/
Byologic v2.3	Protein Metrics	https://www.proteinmetrics.com/products/byologic/