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. 2018 Oct 1;18:940. doi: 10.1186/s12885-018-4840-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Heatmap and consensus sequence of CDR3 region of 462 EBV transformed normal B lymphocytes. a. Heatmap of IGH, IGK/IGL and TRA/TRB in 462 EBV transformed normal B lymphocyte cell lines. Green color line in the heatmap represents the gene expression of the particular sample, with a line drawn more towards the right, indicating a higher level of expression. b. Length of the CDR3 region (amino acids sequence, AAs) of the dominant clone in 462 EBV transformed normal B lymphocytes. c. Consensus sequence of the CDR3 region of the dominant clone in 462 EBV transformed normal B lymphocyte cell lines. Sequences of the CDR3 region were aligned using ClustalW, and the consensus sequences were plotted using weblogo