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. 2018 Oct 1;18:940. doi: 10.1186/s12885-018-4840-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Clonotypes of IGH, IGK/L in 462 samples of EBV transformed normal B lymphocytes. a. Number of clonotypes based on IGH vs IGK; IGH vs IGL; and IGK vs IGL in 462 EBV transformed normal B lymphocyte lines. Right panel is the blow-up of the picture (left panel, clonal type 0–30). b. Correlation of the number of clonal types based on IGH vs IGK; IGH vs IGL; and IGK vs IGL in 462 samples of EBV transformed normal B lymphocytes. c. Phylogenetic trees inferred based on CDR3 region of either IGK or IGL rearrangements of the dominant clone of 462 EBV transformed normal B lymphocyte cell lines, using Neighbor-Joining method conducted with MEGA7. Evolutionary distances are computed using the Poisson correction method and are in the units of the number of amino acid substitutions per site