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. 2018 Oct 2;13:36. doi: 10.1186/s40248-018-0149-0

Table 3.

Potential indicators for do-not-hospitalize AECOPD patients or hospitalization in a general ward or in a respiratory or medical intensive care units (ICU)

Variables Do-not-hospitalize General ward Respiratory or medical ICU
Insufficient home support X
Good response to initial medical management X
Failed response to initial medical management X
Fewer symptoms (dyspnea on effort, RR < 30 breaths/min, SatO2 > 90%, no confusion, no drowsiness) X
Severe symptoms (resting dyspnea, RR ≥ 30 breaths/min, SatO2 ≤ 90%, confusion, drowsiness) X
Very severe symptoms (dyspnea) that respond inadequately to initial emergency therapy X
Presence of serious comorbidities (e.g. heart failure, newly occurring arrhythmias, etc.) X
Onset of new physical signs (e.g. cyanosis, peripheral edema) X
Acute respiratory failure (without use of accessory respiratory muscles and change in mental status) X
Acute respiratory failure (with use of accessory respiratory muscles and change in mental status) X
Persistent or worsening hypoxemia (PO2 < 40 mmHg) and/or severe respiratory acidosis (pH < 7.25) X
Need for IMV X
Hemodynamic instability (need for vasopressors) X

Modified from report [1]. The cross mark identifies the correct setting

Abbreviations: RR indicates respiratory rate, SatO2 oxygen saturation, PaO2 partial arterial oxygen pressure, IMV invasive mechanical ventilation