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. 2018 Oct 1;16:269. doi: 10.1186/s12967-018-1642-0

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Mutational landscape and tumor mutation burden in WES cohort. a Frequency and types of mutations in 15 genes identified by WES. Different mutations and subtypes are colored. Mutations are shown on left (%). b Tumor mutation burden (mutations/MB) in 16 PTMC