Table 1.
Top 20 significantly differentially expressed protein coding genes between pRT responsive and non-responsive tumor samples
| # | Gene Symbol | Gene Name | FDR-adjusted q-value | Fold Change | Super-Pathways |
|---|---|---|---|---|---|
| 1 | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | 0.03715 ## | 0.10 | protein glycosylation |
| 2 | C6orf105 (ADTRP) | chromosome 6 open reading frame 105 (Androgen-Dependent TFPI-Regulating Protein) | 0.03715 ## | 0.17 | No Data Available |
| 3 | RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.03781 ## | 0.18 | Immune System |
| 4 | A1CF | APOBEC1 complementation factor | 0.03874 ## | 0.17 | mRNA Editing and Processing of Capped Intron-Containing Pre-mRNA |
| 5 | MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.03874 ## | 0.25 | MAPK signaling pathway |
| 6 | CHD5 | chromodomain helicase DNA binding protein 5 | 0.05133 # | 0.15 | ATP-dependent helicase activity |
| 7 | LAS1L | LAS1-like (S. cerevisiae) | 0.05209 # | 0.19 | biogenesis of the 60S ribosomal subunit. |
| 8 | DEFB128 | defensin, beta 128 | 0.05781 # | 0.29 | Immune System |
| 9 | ENHO | energy homeostasis associated | 0.05781 # | 0.23 | metabolism |
| 10 | CECR9 | cat eye syndrome chromosome region, candidate 9 (non-protein coding) | 0.05781 # | 0.20 | unknown |
| 11 | IDO1 | indoleamine 2,3-dioxygenase 1 | 0.05781 # | 0.20 | Tryptophan metabolism |
| 12 | LRRC55 | leucine rich repeat containing 55 | 0.05788 # | 0.14 | ion channel |
| 13 | ROGDI | rogdi homolog (Drosophila) | 0.05788 # | 0.26 | unknown |
| 14 | KRT25 | keratin 25 | 0.05796 # | 0.22 | cytoskeleton |
| 15 | LAMA4 | laminin, alpha 4 | 0.05798 # | 0.25 | Focal Adhesion, ECM-receptor interaction |
| 16 | PLA2G2C | phospholipase A2, group IIC | 0.05798 # | 0.15 | alpha-Linolenic acid metabolism and Glycerophospholipid biosynthesis |
| 17 | CCDC114 | coiled-coil domain containing 114 | 0.05798 # | 0.25 | cell motility |
| 18 | CNGB1 | cyclic nucleotide gated channel beta 1 | 0.05798 # | 0.27 | cAMP binding and intracellular cAMP activated cation channel activity |
| 19 | PRSS53 | protease, serine, 53 | 0.05798 # | 0.30 | serine-type endopeptidase activity |
| 20 | GSG1 | germ cell associated 1 | 0.05798 # | 0.22 | RNA polymerase binding |
FDR – false discovery rate; Fold change is shown on a linear scale
#q-value < 0.1; ##q-value < 0.05