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. 2018 Oct 1;19:345. doi: 10.1186/s12859-018-2392-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — GPCRs (a) and endogenous peptidergic ligands (b) and the highest stage in global pharma pipeline. In each panel, the leftmost chart shows the distribution of highest stage (post-clinical, clinical trial, pre-clinical, none) by target type while the other two charts show such distribution among the gene-disease pairs within the Open Targets platform stratified by corresponding overall score (< 0.5, middle; ≥0.5 right)