Table 2.
The clinical characteristics of participants
| Training set | Validation set | |||||||
|---|---|---|---|---|---|---|---|---|
| Healthy controls | Healthy OSAHS | OSAHS with arterial hypertension | P value | Healthy controls | Healthy OSAHS | OSAHS with arterial hypertension | P value | |
| Number | 5 | 5 | 5 | 15 | 15 | 15 | ||
| Age, (years) | 39.4 ± 1.69 | 40.6 ± 3.17 | 43.8 ± 1.24 | 0.37 | 43.4 ± 2.1 | 43 ± 2.51 | 43.6 ± 2.33 | 0.98 |
| Male, n (%) | 5 (100%) | 5 (100%) | 5 (100%) | – | 11 (73.33%) | 13 (86.67%) | 12 (80%) | 0.68 |
| BMI, (kg/m2) | 23.5 ± 0.42 | 25.18 ± 1.18 | 25.99 ± 0.38 | 0.1 | 24.57 ± 0.46 | 25.56 ± 0.38 | 26.16 ± 0.56 | 0.07 |
| Smoker, n (%) | 2 (40%) | 1 (20%) | 1 (20%) | 0.76 | 1 (6%) | 2 (13%) | 4 (27%) | 0.32 |
| Drinker, n (%) | 0 | 2 (40%) | 2 (40%) | 0.3 | 2 (13%) | 4 (27%) | 7 (47%) | 0.13 |
| Cholesterol, (mmol/L) | 4.42 ± 0.27 | 4.4 ± 0.14 | 3.86 ± 0.4 | 0.35 | 4.37 ± 0.19 | 4.42 ± 0.16 | 4.4 ± 0.24 | 0.99 |
| Triglycerides, (mmol/L) | 0.87 ± 0.05 | 1.44 ± 0.15 | 1.56 ± 0.25 | 0.04 | 1.23 ± 0.13 | 1.5 ± 0.13 | 1.48 ± 0.12 | 0.25 |
| HDL, (mmol/L) | 1.36 ± 0.14 | 0.95 ± 0.09 | 0.86 ± 0.09 | 0.02 | 1.26 ± 0.06 | 1 ± 0.03 | 1.01 ± 0.05 | < 0.001 |
| LDL, (mmol/L) | 2.55 ± 0.15 | 2.88 ± 0.14 | 2.32 ± 0.35 | 0.28 | 2.45 ± 0.17 | 2.8 ± 0.13 | 2.85 ± 0.2 | 0.2 |
| Glucose, (mmol/L) | 4.4 ± 0.1 | 4.54 ± 0.15 | 4.72 ± 0.14 | 0.25 | 4.78 ± 0.12 | 4.93 ± 0.12 | 4.92 (4.7,5.2) | 0.35 |
| HbA1c, (%) | 5.34 ± 0.17 | 5.56 ± 0.13 | 5.52 ± 0.08 | 0.47 | 5.33 ± 0.11 | 5.55 ± 0.06 | 5.46 ± 0.09 | 0.21 |
| ESS | 3 ± 1.48 | 13.8 ± 2.71 | 13.6 ± 2.09 | < 0.001 | 7.27 ± 1.43 | 13.13 ± 1.65 | 8.6 ± 1.21 | < 0.05 |
| AHI, (events/hour) | 1.96 ± 0.52 | 39.27 ± 6.14 | 45.27 ± 8.2 | < 0.001 | 4.52 ± 0.56 | 47.44 ± 4.92 | 43.46 ± 5.25 | < 0.001 |
| Mean SaO2, % | 97 (96,97) | 92.8 ± 1.59 | 93.8 ± 0.66 | < 0.05 | 96 (95.97) | 92.47 ± 0.97 | 94 ± 0.5 | < 0.001 |
| Minimum SaO2, % | 92.6 ± 1.08 | 69.4 ± 3.04 | 74.6 ± 4.61 | < 0.001 | 90.4 ± 0.58 | 74 (60,82) | 72.87 ± 2.02 | < 0.001 |
OSAHS Obstructive sleep apnea hypopnea syndrome, BMI Body mass index, AHI Apnea hypopnea index, SaO2 Oxygen saturation, ESS Epworth Sleepiness Scale, HDL High density lipoprotein, LDL Low density lipoprotein, HbA1c Glycosylated hemoglobin