Table 1.
Characteristics of survivors and non-survivors
| All patients (%) n=350 |
Survivors (%) n=312 |
Non-Survivors (%) n=38 |
P value | |
|---|---|---|---|---|
| Age(years) | 58.53±19.1 | 58.59±19.2 | 58.03±18.9 | 0.86 |
| Males | 204 (58.3) | 181(58.0) | 23(60.5) | 0.7 |
| Comorbidity | ||||
| Diabetes Mellitus | 30(8.57) | 27(8.6) | 3(7.8) | 0.87 |
| Chronic heart disease | 100(28.57) | 91(29.1) | 9(23.6) | 0.48 |
| Chronic liver disease | 22(6.29) | 20(6.4) | 2(5.2) | 0.78 |
| Chronic renal disease | 47(13.43) | 40(12.8) | 7(18.4) | 0.34 |
| Malignant disease | 26(7.43) | 24(7.6) | 2(5.2) | 0.59 |
| History of Shock | 17(4.86) | 15(4.8) | 2(5.2) | 0.9 |
| COPD | 22(6.29) | 18(5.7) | 4(10.5) | 0.25 |
| Cerebrovascular disease | 39(11.14) | 35(11.2) | 4(10.5) | 0.9 |
| Antimicrobial treatment before admission | 79(22.6) | 70(22.4) | 9(23.7) | 1 |
| Signs and symptoms | ||||
| Cough | 268(76.6) | 260(83.3) | 28(73.6) | 0.14 |
| Chest pain | 116(33.1) | 106(33.9) | 10(26.3) | 0.34 |
| Expectoration | 168(48) | 148(47.4) | 20(52.6) | 0.54 |
| Dyspnea | 249(71.1) | 221(70.8) | 28(73.6) | 0.72 |
| Chills | 124(35.4) | 109(34.9) | 15(39.4) | 0.58 |
| Headaches | 75(21.4) | 58(18.5) | 17(44.7) | <0.001 |
| Myalgia | 79(22.6) | 71(22.7) | 8(21) | 0.8 |
| Crackles | 114(32.6) | 102(32.6) | 12(31.5) | 0.89 |
| Fever | 110(31.4) | 96(30.7) | 14(36.8) | 0.45 |
| Confusion | 5(1.4) | 1(0.3) | 4(10.5) | <0.001 |
| CCI class | ||||
| 0-2 | 129(36.8) | 116(37.1) | 13(34.2) | 0.7 |
| 3-5 | 180(51.4) | 161(51.6) | 19(50) | |
| >5 | 41(11.7) | 35(11.2) | 6(15.7) | |
| CRP1 (mg/L) | 65.3±84.7 | 66.3±85.2 | 57.1±81.3 | 0.53 |
| CRP3 (mg/L) | 56.4±77.4 | 50±66.4 | 109.1±128.4 | <0.001 |
| CRP3c | 556.6±5056.3 | 575.2±5334.2 | 401.2±1242.4 | 0.843 |
| CRP3c<0 | 223(63.7) | 214(68.5) | 9(23.6) | <0.001 |
| CRP5(mg/L) | 44.8±68.5 | 37.9±61 | 102.1±96.9 | <0.001 |
| CRP5c | 429.2±3489.6 | 429.2±3670.1 | 429.3±1207.6 | 0.999 |
| CRP5c<0 | 222(63.4) | 213(68.2) | 9(23.6) | <0.001 |
| PCT1 (ng/mL) | 1.8±7.1 | 1.8±7.3 | 1.9±5.5 | 0.96 |
| PCT3 (ng/mL) | 1.7±6.3 | 1.4±4.4 | 4.1±14.5 | 0.012 |
| PCT3c | 791.2±2653.8 | 793.3±2672.6 | 774.1±2528.7 | 0.966 |
| PCT3c<0 | 174(49.7) | 157(50.3) | 17(44.7) | 0.52 |
| PCT5 (ng/mL) | 1.2±3.7 | 0.8±2 | 4.3±9.3 | <0.001 |
| PCT5c | 695.3±2463 | 589.9±2298.2 | 1555±3454.4 | 0.022 |
| PCT5c<0 | 179(51.1) | 170(54.4) | 9(23.6) | <0.001 |
| WBC1 | 10.4±8 | 10.1±7.2 | 12.6±12.8 | 0.081 |
| WBC3 | 9.5±5 | 9.2±5 | 10.8±4.7 | 0.112 |
| WBC5 | 10.5±6.6 | 10.4±7 | 10.6±4.7 | 0.932 |
| CURB class | ||||
| 0-2 | 289 | 256 | 33 | 0.46 |
| 3-5 | 61 | 56 | 5 | |
Data are presented as means ±SD, or n (%), CRP, C-reactive protein; CURB-65, confusion, urea > 7 mmol/L, respiratory rate≥30 breaths/min, low blood pressure (systolic<90mm Hg or diastolic≤60 mm Hg) and age≥65 years
PCT procalcitonin, COPD Chronic Obstructive Pulmonary Disease, SD standard deviation, WBC white blood cell, CRP3c 5c: CRP clearance on day3, day5 PCT3c, 5c PCT clearance on day 3, day 5