Table 3.
Univariate and multivariate analyses of biomarkers for initial treatment failure
| Initial treatment failure | Univariate Odds ratio(95% CI) | Univariate P-value | Multivariate Odds ratio(95% CI) | Multivariate P-value | ||
|---|---|---|---|---|---|---|
| Yes | No | |||||
| CRP1 (mg/L) | 71±88.7 | 64±83.9 | 0.999(0.996-1.003) | 0.55 | 1.008(1.001-1.013) | 0.009 |
| CRP3 (mg/L) | 89.2±107.6 | 48.9±66.8 | 0.995(0.991-0.998) | 0.001 | 0.992(0.985-0.999) | 0.035 |
| CRP3c | 801.8±3644.9 | 501±5328.5 | 1 | 0.673 | 1(0.999-1) | 0.33 |
| CRP5(mg/L) | 79.7±96.3 | 37.2±58.3 | 0.993(0.989-0.997) | <0.001 | 0.996(0.989-1.001) | 0.15 |
| CRP5c | 682.9±2888.4 | 371.7±3614.2 | 1 | 0.534 | 1(0.999-1) | 0.299 |
| PCT1 (ng/mL) | 4.6±13.6 | 1.2±4.2 | 0.936(0.892-0.983) | 0.009 | 0.89(0.82-0.965) | 0.005 |
| PCT3 (ng/mL) | 2.8±11.2 | 1.4±4.5 | 0.975(0.941-1.01) | 0.163 | 1.134(1.017-1.263) | 0.022 |
| PCT3c | 469.1±1972.7 | 865.2±2784.4 | 1 | 0.293 | 1(0.999-1) | 0.403 |
| PCT5 (ng/mL) | 2.8±7.3 | 0.8±2.1 | 0.868(0.892-0.983) | 0.005 | 0.851(0.751-0.963) | 0.01 |
| PCT5c | 1013.8±2761.2 | 622.1±2388.7 | 1 | 0.268 | 1(0.999-1) | 0.658 |
a Variable(s) entered on step 1: CRP1, CRP3, CRP3c, CRP5, CRP5c, PCT1, PCT3, PCT3c, PCT5, PCT5c, and CURB65