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Budlein A inhibits MSU-induced mononuclear cell and neutrophil recruitment to the knee joint. Fifteen hours after the injection of MSU crystals, knee joint wash was collected for determination of total leukocytes (A), neutrophils (B), and mononuclear cells (C) using Neubauer chamber (A) and Rosenfeld stained slices (B,C). ∗p < 0.05 vs. saline group; #p < 0.05 vs. 0 mg/kg group, one-way ANOVA followed by Tukey’s post hoc.
