Table.
Characteristic | Treatment Groupa | P Value | |
---|---|---|---|
Taper (n = 57) | Maintenance (n = 56) | ||
Age, mean (95% CI), y | 30.3 (28.0–32.6) | 30.5 (27.9–33.1) | .88 |
Male sex | 34 (60) | 31 (55) | .64 |
White race | 56 (98) | 52 (93) | .16 |
Hispanic ethnicity | 4 (7) | 4 (7) | .68 |
Full-time employmentb | 23 (40) | 25/53 (47) | .47 |
Educational level beyond high schoolb | 36 (63) | 35/53 (66) | .75 |
Never marriedb | 37 (65) | 34/53 (61) | .93 |
Duration of opioid dependence, mean (95% CI), y | 4.5 (3.3–5.6) | 4.9 (3.7–6.0) | .63 |
Provided an opioid-positive urine sample during induction and stabilization period | 16 (28) | 13 (23) | .55 |
Patient-reported illicit opioid use in the past 30 d, mean (95% CI), d | 20.8 (18.9–22.7) | 21.1 (19.2–23.0) | .88 |
Cocaine abuse | 5 (9) | 8 (14) | .36 |
Route of opioid administration, nasal or oral | 56 (98) | 56 (100) | .32 |
Prior therapy | |||
Attempted opioid detoxification | 8 (14) | 6 (11) | .54 |
Formal treatment for an opioid use disorderc | 18 (33) | 14 (25) | .37 |
Use of other substances in past 30 d, mean (95% CI), d | |||
Alcohol | 2.4 (0.8–4.1) | 5.6 (3.8–7.1) | .01 |
Cocaine | 0.4 (0.2–1.0) | 0.9 (0.3–1.5) | .23 |
Duration of induction and stabilization therapy, mean (95% CI), d | 11.7 (10.9–12.4) | 12.3 (11.6–13.1) | .24 |
Buprenorphine treatment was administered as a tablet formulation of buprenorphine hydrochloride and naloxone hydrochloride in a 4:1 ratio. Unless otherwise indicated, data are expressed as number (percentage) of patients.
Includes 53 patients in the maintenance group.
Includes 55 patients in the taper group.