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. Author manuscript; available in PMC: 2018 Oct 2.
Published in final edited form as: JAMA Intern Med. 2014 Dec;174(12):1947–1954. doi: 10.1001/jamainternmed.2014.5302

Table.

Baseline Demographic and Clinical Characteristics of Patients With Prescription Opioid Dependence Receiving Buprenorphine Treatment in Primary Care

Characteristic Treatment Groupa P Value
Taper (n = 57) Maintenance (n = 56)
Age, mean (95% CI), y 30.3 (28.0–32.6) 30.5 (27.9–33.1) .88
Male sex 34 (60) 31 (55) .64
White race 56 (98) 52 (93) .16
Hispanic ethnicity 4 (7) 4 (7) .68
Full-time employmentb 23 (40) 25/53 (47) .47
Educational level beyond high schoolb 36 (63) 35/53 (66) .75
Never marriedb 37 (65) 34/53 (61) .93
Duration of opioid dependence, mean (95% CI), y 4.5 (3.3–5.6) 4.9 (3.7–6.0) .63
Provided an opioid-positive urine sample during induction and stabilization period 16 (28) 13 (23) .55
Patient-reported illicit opioid use in the past 30 d, mean (95% CI), d 20.8 (18.9–22.7) 21.1 (19.2–23.0) .88
Cocaine abuse 5 (9) 8 (14) .36
Route of opioid administration, nasal or oral 56 (98) 56 (100) .32
Prior therapy
 Attempted opioid detoxification 8 (14) 6 (11) .54
 Formal treatment for an opioid use disorderc 18 (33) 14 (25) .37
Use of other substances in past 30 d, mean (95% CI), d
 Alcohol 2.4 (0.8–4.1) 5.6 (3.8–7.1) .01
 Cocaine 0.4 (0.2–1.0) 0.9 (0.3–1.5) .23
Duration of induction and stabilization therapy, mean (95% CI), d 11.7 (10.9–12.4) 12.3 (11.6–13.1) .24
a

Buprenorphine treatment was administered as a tablet formulation of buprenorphine hydrochloride and naloxone hydrochloride in a 4:1 ratio. Unless otherwise indicated, data are expressed as number (percentage) of patients.

b

Includes 53 patients in the maintenance group.

c

Includes 55 patients in the taper group.