Table 3.
LY2510924 related non-hematological toxicities (n = 11).
| Toxicity | Grade 1–2, n (%) | Grade 3–4, n (%) | Total, n (%) |
|---|---|---|---|
| Alopecia | 1 (9) | 1 (9) | |
| Anorexia | 1 (9) | 1 (9) | 2 (18) |
| Atrial fibrillation | 1 (9) | 1 (9) | |
| Bacteremia | 1 (9) | 1 (9) | |
| Bilirubin elevation | 1 (9) | 1 (9) | |
| Confusion | 1 (9) | 1 (9) | |
| Constipation | 3 (27) | 3 (27) | |
| Dry eyes | 1 (9) | 1 (9) | |
| Diarrhea | 5 (45) | 1 (9) | 6 (54) |
| Dizziness | 1 (9) | 1 (9) | |
| Eye pain | 1 (9) | 1 (9) | |
| Eye hemorrhage | 1 (9) | 1 (9) | |
| Fall | 1 (9) | 1 (9) | |
| Fatigue | 1 (9) | 1 (9) | |
| Gait disturbance | 1 (9) | 1 (9) | |
| Gastrointestinal disorders | 1 (9) | 1 (9) | |
| Headache | 1 (9) | 1 (9) | |
| Lung infection | 1 (9) | 1 (9) | |
| Rash, maculopapular | 1 (9) | 1 (9) | 2 (18) |
| Pruritis | 3 (27) | 3 (27) | |
| Mucositis | 3 (27) | 1 (9) | 4 (36) |
| Myelosuppression | 1 (9) | 1 (9) | |
| Nausea/vomiting | 5 (45) | 5 (45) | |
| Neuropathy | 1 (9) | 1 (9) | |
| Oral pain | 1 (9) | 1 (9) | |
| QTc prolongation | 1 (9) | 1 (9) | |
| Sweet syndrome | 1 (9) | 1 (9) | |
| Transaminase elevation | 1 (9) | 1 (9) | |
| Urinary retention | 1 (9) | 1 (9) | |
| Total | 38 | 9 | 47 |