Table 3.
Comparison of rs1801278 (alleles and genotypes) in all the studied T2DM patients and healthy controls
| Control (N=120)
|
Cases (N=100)
|
P | OR | 95% CI | ||||
|---|---|---|---|---|---|---|---|---|
| N | % | N | % | |||||
| GG | 108 | 90 | 70 | 70.0 | – | R | – | – |
| GA | 12 | 10 | 26 | 26.0 | 0.025 | 3.343 | 1.162 | 9.617 |
| AA | 0 | 0 | 4 | 4.0 | 0.999 | – | – | – |
| GA+AA | 12 | 10 | 30 | 30.0 | 0.011 | 3.857 | 1.366 | 10.890 |
| GA+GG | 120 | 100 | 96 | 96 | 0.041 | – | – | – |
| GG+AA | 108 | 90 | 74 | 74 | 0.002 | 0.489 | 0.310 | 0.770 |
| G | 228 | 95.0 | 166 | 83.0 | – | R | – | – |
| A | 12 | 5.0 | 34 | 17.0 | 0.004 | 3.892 | 1.471 | 10.294 |
Note: Logistic regression test was used.
Abbreviations: R, reference; T2DM, type 2 diabetes mellitus.